SMTL ID : 1ti8.1

H7 Haemagglutinin

Coordinates

PDB Format

Method

X-RAY DIFFRACTION 3.00 Å

Oligo State

hetero-3-3-mer

Ligands

3 x NDG: 2-acetamido-2-deoxy-alpha-D-glucopyranose(Non-covalent)

NDG.1: 5 residues within 4Å: Chain A: N.287, S.288, R.289 Ligands: MAN.2, NAG.8 1 PLIP interactions: 1 interactions with chain A Hydrogen bonds: A:R.289 NDG.9: 5 residues within 4Å: Chain C: N.287, S.288, R.289 Ligands: MAN.10, NAG.16 1 PLIP interactions: 1 interactions with chain C Hydrogen bonds: C:R.289 NDG.17: 5 residues within 4Å: Chain E: N.287, S.288, R.289 Ligands: MAN.18, NAG.24 1 PLIP interactions: 1 interactions with chain E Hydrogen bonds: E:R.289

15 x MAN: alpha-D-mannopyranose(Non-covalent)(Non-functional Binders)

MAN.2: 4 residues within 4Å: Ligands: NDG.1, MAN.3, MAN.4, MAN.6 No protein-ligand interaction detected (PLIP) MAN.3: 2 residues within 4Å: Ligands: MAN.2, MAN.4 No protein-ligand interaction detected (PLIP) MAN.4: 5 residues within 4Å: Chain A: R.79, S.259 Ligands: MAN.2, MAN.3, MAN.5 4 PLIP interactions: 4 interactions with chain A Hydrogen bonds: A:R.79, A:R.79, A:S.259, A:S.259 MAN.5: 1 residues within 4Å: Ligands: MAN.4 No protein-ligand interaction detected (PLIP) MAN.6: 1 residues within 4Å: Ligands: MAN.2 No protein-ligand interaction detected (PLIP) MAN.10: 4 residues within 4Å: Ligands: NDG.9, MAN.11, MAN.12, MAN.14 No protein-ligand interaction detected (PLIP) MAN.11: 2 residues within 4Å: Ligands: MAN.10, MAN.12 No protein-ligand interaction detected (PLIP) MAN.12: 5 residues within 4Å: Chain C: R.79, S.259 Ligands: MAN.10, MAN.11, MAN.13 4 PLIP interactions: 4 interactions with chain C Hydrogen bonds: C:R.79, C:R.79, C:S.259, C:S.259 MAN.13: 1 residues within 4Å: Ligands: MAN.12 No protein-ligand interaction detected (PLIP) MAN.14: 1 residues within 4Å: Ligands: MAN.10 No protein-ligand interaction detected (PLIP) MAN.18: 4 residues within 4Å: Ligands: NDG.17, MAN.19, MAN.20, MAN.22 No protein-ligand interaction detected (PLIP) MAN.19: 2 residues within 4Å: Ligands: MAN.18, MAN.20 No protein-ligand interaction detected (PLIP) MAN.20: 5 residues within 4Å: Chain E: R.79, S.259 Ligands: MAN.18, MAN.19, MAN.21 4 PLIP interactions: 4 interactions with chain E Hydrogen bonds: E:R.79, E:R.79, E:S.259, E:S.259 MAN.21: 1 residues within 4Å: Ligands: MAN.20 No protein-ligand interaction detected (PLIP) MAN.22: 1 residues within 4Å: Ligands: MAN.18 No protein-ligand interaction detected (PLIP)

6 x NAG: 2-acetamido-2-deoxy-beta-D-glucopyranose(Non-functional Binders)(Non-covalent)

NAG.7: 1 residues within 4Å: Chain A: N.26 1 PLIP interactions: 1 interactions with chain A Hydrogen bonds: A:N.26 NAG.8: 5 residues within 4Å: Chain B: E.72, K.75, N.79, N.82 Ligands: NDG.1 6 PLIP interactions: 4 interactions with chain B, 2 interactions with chain A Hydrogen bonds: B:E.72, A:S.288, A:S.288 Water bridges: B:E.72, B:K.75, B:N.82 NAG.15: 1 residues within 4Å: Chain C: N.26 1 PLIP interactions: 1 interactions with chain C Hydrogen bonds: C:N.26 NAG.16: 5 residues within 4Å: Chain D: E.72, K.75, N.79, N.82 Ligands: NDG.9 6 PLIP interactions: 4 interactions with chain D, 2 interactions with chain C Hydrogen bonds: D:E.72, C:S.288, C:S.288 Water bridges: D:E.72, D:K.75, D:N.82 NAG.23: 1 residues within 4Å: Chain E: N.26 1 PLIP interactions: 1 interactions with chain E Hydrogen bonds: E:N.26 NAG.24: 5 residues within 4Å: Chain F: E.72, K.75, N.79, N.82 Ligands: NDG.17 6 PLIP interactions: 4 interactions with chain F, 2 interactions with chain E Hydrogen bonds: F:E.72, E:S.288, E:S.288 Water bridges: F:E.72, F:K.75, F:N.82

Links

RCSB   PDBe   PDBj   PDBsum   CATH   PLIP

Citation

Russell, R.J. et al., H1 and H7 influenza haemagglutinin structures extend a structural classification of haemagglutinin subtypes. Virology (2004)

Release Date

2005-06-21

Peptides

hemagglutinin: ACE
hemagglutinin: BDF

SMTL:PDB

SMTL Chain Id:
PDB Chain Id:

A
A

C
A

E
A

B
B

D
B

F
B

hemagglutinin

hemagglutinin