SMTL ID : 1rvt.1

1930 H1 Hemagglutinin in complex with LSTC

Coordinates

PDB Format

Method

X-RAY DIFFRACTION 2.50 Å

Oligo State

hetero-3-3-mer

Ligands

2 x GAL- SIA: N-acetyl-alpha-neuraminic acid-(2-6)-beta-D-galactopyranose(Non-covalent)

GAL-SIA.1: 12 residues within 4Å: Chain A: Y.95, R.134, V.136, T.137, A.138, W.154, H.184, P.187, L.195, K.223, G.226, Q.227 7 PLIP interactions: 7 interactions with chain A Hydrogen bonds: A:K.223, A:K.223, A:G.226, A:Y.95, A:V.136, A:T.137, A:A.138, A:Q.227, A:Q.227 Hydrophobic interactions: A:L.195 GAL-SIA.3: 13 residues within 4Å: Chain E: Y.95, R.134, V.136, T.137, A.138, W.154, V.156, H.184, P.187, L.195, K.223, G.226, Q.227 8 PLIP interactions: 8 interactions with chain E Hydrogen bonds: E:K.223, E:K.223, E:G.226, E:Y.95, E:V.136, E:T.137, E:A.138, E:Q.227, E:Q.227, E:Q.227 Water bridges: E:A.228 Hydrophobic interactions: E:L.195

1 x BGC- GAL- NAG- GAL- SIA: N-acetyl-alpha-neuraminic acid-(2-6)-beta-D-galactopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-3)-beta-D-galactopyranose-(1-4)-beta-D-glucopyranose

BGC-GAL-NAG-GAL-SIA.2: 17 residues within 4Å: Chain C: Y.95, R.134, V.136, T.137, A.138, W.154, V.156, H.184, P.187, T.190, D.191, Q.193, S.194, L.195, K.223, G.226, Q.227 2 PLIP interactions: 2 interactions with chain C Hydrogen bonds: C:K.223, C:K.223, C:G.226, C:Q.227, C:Y.95, C:V.136, C:T.137, C:A.138, C:Q.227, C:Q.227, C:D.191 Hydrophobic interactions: C:L.195, C:L.195 Water bridges: C:Q.193, C:Q.193

3 x NDG: 2-acetamido-2-deoxy-alpha-D-glucopyranose(Non-covalent)

NDG.4: 9 residues within 4Å: Chain A: N.68, P.69, E.70, N.91, C.94, A.139, C.140, P.141, R.225 6 PLIP interactions: 6 interactions with chain A Hydrophobic interactions: A:P.69 Hydrogen bonds: A:N.68, A:N.91, A:R.225, A:R.225 Salt bridges: A:R.225 NDG.5: 8 residues within 4Å: Chain C: N.68, E.70, N.91, C.94, A.139, C.140, P.141, R.225 5 PLIP interactions: 5 interactions with chain C Hydrogen bonds: C:N.68, C:N.91, C:R.225, C:R.225 Salt bridges: C:R.225 NDG.6: 8 residues within 4Å: Chain E: N.68, P.69, E.70, N.91, C.94, C.140, P.141, R.225 7 PLIP interactions: 7 interactions with chain E Hydrogen bonds: E:N.68, E:N.91, E:R.225, E:R.225 Water bridges: E:E.70, E:P.141 Salt bridges: E:R.225

Links

RCSB   PDBe   PDBj   PDBsum   CATH   PLIP

Citation

Gamblin, S.J. et al., The structure and receptor binding properties of the 1918 influenza hemagglutinin. Science (2004)

Release Date

2004-03-30

Peptides

hemagglutinin: ACE
hemagglutinin: BDF

SMTL:PDB

SMTL Chain Id:
PDB Chain Id:

A
H

C
J

E
L

B
I

D
K

F
M

hemagglutinin

hemagglutinin

Related Entries With Identical Sequence