SMTL ID : 1rd8.1

Crystal Structure of the 1918 Human H1 Hemagglutinin Precursor (HA0)

Coordinates

PDB Format

Method

X-RAY DIFFRACTION 3.00 Å

Oligo State

hetero-3-3-mer

Ligands

2 x NAG- NAG- BMA: beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose(Post Translational Modification)

NAG-NAG-BMA.1: 6 residues within 4Å: Chain A: N.72, E.74, E.94, N.95, C.98, R.229 No protein-ligand interaction detected (PLIP) NAG-NAG-BMA.3: 6 residues within 4Å: Chain E: N.72, E.74, E.94, N.95, C.98, R.229 2 PLIP interactions: 2 interactions with chain E Hydrogen bonds: E:R.229, E:R.229

1 x NAG- NAG- BMA- MAN: alpha-D-mannopyranose-(1-3)-beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose(Post Translational Modification)

NAG-NAG-BMA-MAN.2: 6 residues within 4Å: Chain C: N.72, E.74, E.94, N.95, C.98, R.229 1 PLIP interactions: 1 interactions with chain C Hydrogen bonds: C:R.229

6 x NAG: 2-acetamido-2-deoxy-beta-D-glucopyranose(Post Translational Modification)(Non-functional Binders)

NAG.4: 2 residues within 4Å: Chain A: N.19 Chain B: I.10 No protein-ligand interaction detected (PLIP) NAG.5: 2 residues within 4Å: Chain A: N.31, T.33 No protein-ligand interaction detected (PLIP) NAG.6: 3 residues within 4Å: Chain B: E.150, N.154, T.156 3 PLIP interactions: 3 interactions with chain B Hydrogen bonds: B:E.150, B:E.150, B:N.154 NAG.8: 3 residues within 4Å: Chain C: T.23, N.31, T.33 No protein-ligand interaction detected (PLIP) NAG.9: 2 residues within 4Å: Chain C: N.295, S.297 No protein-ligand interaction detected (PLIP) NAG.10: 1 residues within 4Å: Chain E: N.31 1 PLIP interactions: 1 interactions with chain E Hydrogen bonds: E:N.31

1 x PO4: PHOSPHATE ION(Post Translational Modification)

PO4.7: 9 residues within 4Å: Chain B: R.116, E.120, K.123 Chain D: R.116, E.120, K.123 Chain F: R.116, E.120, K.123 7 PLIP interactions: 2 interactions with chain F, 3 interactions with chain D, 2 interactions with chain B Salt bridges: F:R.116, F:K.123, D:R.116, D:K.123, B:R.116, B:K.123 Hydrogen bonds: D:E.120

Links

RCSB   PDBe   PDBj   PDBsum   CATH   PLIP

Citation

Stevens, J. et al., Structure of the Uncleaved Human H1 Hemagglutinin from the Extinct 1918 Influenza Virus. Science (2004)

Release Date

2004-03-23

Peptides

hemagglutinin: ACE
hemagglutinin: BDF

SMTL:PDB

SMTL Chain Id:
PDB Chain Id:

A
A

C
C

E
E

B
B

D
D

F
F

hemagglutinin

hemagglutinin