SMTL ID : 1qot.1

lectin UEA-II complexed with fucosyllactose and fucosylgalactose

Coordinates

PDB Format

Method

X-RAY DIFFRACTION 3.00 Å

Oligo State

homo-tetramer

Ligands

3 x GAL- FUC: alpha-L-fucopyranose-(1-2)-beta-D-galactopyranose(Non-covalent)

GAL-FUC.1: 10 residues within 4Å: Chain A: V.85, D.86, S.104, A.105, G.106, Y.130, Y.135, G.219, N.220, E.223 4 PLIP interactions: 4 interactions with chain A Hydrogen bonds: A:S.104, A:A.105, A:G.106, A:D.86, A:G.219, A:E.223, A:E.223 GAL-FUC.2: 12 residues within 4Å: Chain B: V.85, D.86, S.104, A.105, G.106, Y.130, Y.135, N.136, W.138, G.219, N.220, E.223 5 PLIP interactions: 5 interactions with chain B Hydrophobic interactions: B:Y.135 Hydrogen bonds: B:S.104, B:S.104, B:A.105, B:G.106, B:N.136, B:D.86, B:N.136, B:G.219, B:E.223, B:E.223 GAL-FUC.4: 11 residues within 4Å: Chain D: V.85, D.86, S.104, A.105, G.106, Y.130, Y.135, N.136, G.219, N.220, E.223 4 PLIP interactions: 4 interactions with chain D Hydrophobic interactions: D:Y.135 Hydrogen bonds: D:S.104, D:S.104, D:A.105, D:G.106, D:D.86, D:N.136, D:G.219, D:E.223

1 x GLC- GAL- FUC: alpha-L-fucopyranose-(1-2)-beta-D-galactopyranose-(1-4)-alpha-D-glucopyranose(Post Translational Modification)

GLC-GAL-FUC.3: 11 residues within 4Å: Chain C: V.85, D.86, S.104, G.106, Y.130, Y.135, N.136, W.138, G.219, N.220, E.223 4 PLIP interactions: 4 interactions with chain C Hydrogen bonds: C:S.104, C:S.104, C:G.106, C:N.136, C:D.86, C:N.136, C:G.219, C:E.223

4 x MN: MANGANESE (II) ION(Non-covalent)(Post Translational Modification)

MN.5: 5 residues within 4Å: Chain A: E.126, D.128, D.139, H.144, S.154 4 PLIP interactions: 4 interactions with chain A Metal complexes: A:E.126, A:D.128, A:D.139, A:H.144 MN.8: 5 residues within 4Å: Chain B: E.126, D.128, D.139, H.144, S.154 4 PLIP interactions: 4 interactions with chain B Metal complexes: B:E.126, B:D.128, B:D.139, B:H.144 MN.11: 5 residues within 4Å: Chain C: E.126, D.128, D.139, H.144, S.154 4 PLIP interactions: 4 interactions with chain C Metal complexes: C:E.126, C:D.128, C:D.139, C:H.144 MN.14: 5 residues within 4Å: Chain D: E.126, D.128, D.139, H.144, S.154 4 PLIP interactions: 4 interactions with chain D Metal complexes: D:E.126, D:D.128, D:D.139, D:H.144

4 x CA: CALCIUM ION(Non-covalent)

CA.6: 4 residues within 4Å: Chain A: D.128, Y.130, N.136, D.139 4 PLIP interactions: 4 interactions with chain A Metal complexes: A:D.128, A:D.128, A:Y.130, A:D.139 CA.9: 4 residues within 4Å: Chain B: D.128, Y.130, N.136, D.139 4 PLIP interactions: 4 interactions with chain B Metal complexes: B:D.128, B:D.128, B:Y.130, B:D.139 CA.12: 5 residues within 4Å: Chain C: D.86, D.128, Y.130, N.136, D.139 4 PLIP interactions: 4 interactions with chain C Metal complexes: C:D.128, C:D.128, C:Y.130, C:D.139 CA.15: 5 residues within 4Å: Chain D: D.86, D.128, Y.130, N.136, D.139 4 PLIP interactions: 4 interactions with chain D Metal complexes: D:D.128, D:D.128, D:Y.130, D:D.139

4 x NAG: 2-acetamido-2-deoxy-beta-D-glucopyranose(Non-covalent)(Post Translational Modification)

NAG.7: 3 residues within 4Å: Chain A: P.100, S.101, S.112 1 PLIP interactions: 1 interactions with chain A Hydrogen bonds: A:S.101 NAG.10: 2 residues within 4Å: Chain B: P.100, S.112 1 PLIP interactions: 1 interactions with chain B Hydrogen bonds: B:S.101 NAG.13: 3 residues within 4Å: Chain C: P.100, S.101, S.112 1 PLIP interactions: 1 interactions with chain C Hydrogen bonds: C:S.101 NAG.16: 2 residues within 4Å: Chain D: S.101, S.112 1 PLIP interactions: 1 interactions with chain D Hydrogen bonds: D:S.101

Links

RCSB   PDBe   PDBj   PDBsum   CATH   PLIP

Citation

Loris, R. et al., Structural Basis of Carbohydrate Recognition by Lectin II from Ulex Europaeus, a Protein with a Promiscuous Carbohydrate Binding Site. J.Mol.Biol. (2000)

Release Date

1999-11-23

Peptides

CHITIN BINDING LECTIN, UEA-II: ABCD

SMTL:PDB

SMTL Chain Id:
PDB Chain Id:

A
A

B
B

C
C

D
D

CHITIN BINDING LECTIN, UEA-II

Related Entries With Identical Sequence