SMTL ID : 1qfu.1

INFLUENZA VIRUS HEMAGGLUTININ COMPLEXED WITH A NEUTRALIZING ANTIBODY

Coordinates

PDB Format

Method

X-RAY DIFFRACTION 2.80 Å

Oligo State

hetero-3-3-3-3-mer

Ligands

3 x NAG- NDG: 2-acetamido-2-deoxy-alpha-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose(Post Translational Modification)(Non-covalent)

NAG-NDG.1: 5 residues within 4Å: Chain A: Q.80, N.81, F.120, I.121, T.122 1 PLIP interactions: 1 interactions with chain A Hydrophobic interactions: A:Q.80 NAG-NDG.6: 5 residues within 4Å: Chain E: Q.80, N.81, F.120, I.121, T.122 1 PLIP interactions: 1 interactions with chain E Hydrophobic interactions: E:Q.80 NAG-NDG.11: 5 residues within 4Å: Chain I: Q.80, N.81, F.120, I.121, T.122 1 PLIP interactions: 1 interactions with chain I Hydrophobic interactions: I:Q.80

3 x NAG- NAG- BMA: beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose(Post Translational Modification)

NAG-NAG-BMA.2: 5 residues within 4Å: Chain A: N.165, T.167 Chain I: S.219, P.221, W.222 1 PLIP interactions: 1 interactions with chain I Hydrogen bonds: I:W.222 NAG-NAG-BMA.7: 5 residues within 4Å: Chain A: S.219, P.221, W.222 Chain E: N.165, T.167 1 PLIP interactions: 1 interactions with chain A Hydrogen bonds: A:W.222 NAG-NAG-BMA.12: 5 residues within 4Å: Chain E: S.219, P.221, W.222 Chain I: N.165, T.167 1 PLIP interactions: 1 interactions with chain E Hydrogen bonds: E:W.222

9 x NAG: 2-acetamido-2-deoxy-beta-D-glucopyranose(Non-covalent)(Post Translational Modification)

NAG.3: 3 residues within 4Å: Chain A: N.38, T.318 Chain B: L.52 2 PLIP interactions: 2 interactions with chain A Hydrogen bonds: A:N.38, A:T.318 NAG.4: 4 residues within 4Å: Chain A: S.45, N.285, V.297, N.298 3 PLIP interactions: 3 interactions with chain A Hydrophobic interactions: A:V.297 Hydrogen bonds: A:V.297, A:N.298 NAG.5: 5 residues within 4Å: Chain B: A.147, E.150, S.151, N.154, T.156 2 PLIP interactions: 2 interactions with chain B Hydrophobic interactions: B:N.154 Hydrogen bonds: B:T.156 NAG.8: 3 residues within 4Å: Chain E: N.38, T.318 Chain F: L.52 2 PLIP interactions: 2 interactions with chain E Hydrogen bonds: E:N.38, E:T.318 NAG.9: 4 residues within 4Å: Chain E: S.45, N.285, V.297, N.298 3 PLIP interactions: 3 interactions with chain E Hydrophobic interactions: E:V.297 Hydrogen bonds: E:V.297, E:N.298 NAG.10: 5 residues within 4Å: Chain F: A.147, E.150, S.151, N.154, T.156 2 PLIP interactions: 2 interactions with chain F Hydrophobic interactions: F:N.154 Hydrogen bonds: F:T.156 NAG.13: 3 residues within 4Å: Chain I: N.38, T.318 Chain J: L.52 2 PLIP interactions: 2 interactions with chain I Hydrogen bonds: I:N.38, I:T.318 NAG.14: 4 residues within 4Å: Chain I: S.45, N.285, V.297, N.298 3 PLIP interactions: 3 interactions with chain I Hydrophobic interactions: I:V.297 Hydrogen bonds: I:V.297, I:N.298 NAG.15: 5 residues within 4Å: Chain J: A.147, E.150, S.151, N.154, T.156 2 PLIP interactions: 2 interactions with chain J Hydrophobic interactions: J:N.154 Hydrogen bonds: J:T.156

Links

RCSB   PDBe   PDBj   PDBsum   CATH   PLIP

Citation

Fleury, D. et al., A complex of influenza hemagglutinin with a neutralizing antibody that binds outside the virus receptor binding site. Nat.Struct.Biol. (1999)

Release Date

1999-04-16

Peptides

PROTEIN (HEMAGGLUTININ (HA1 CHAIN)): AEI
PROTEIN (HEMAGGLUTININ (HA2 CHAIN)): BFJ
PROTEIN (IMMUNOGLOBULIN IGG1-KAPPA ANTIBODY (LIGHT CHAIN)): CGK
PROTEIN (IMMUNOGLOBULIN IGG1-KAPPA ANTIBODY (HEAVY CHAIN)): DHL

SMTL:PDB

SMTL Chain Id:
PDB Chain Id:

A
A

E
A

I
A

B
B

F
B

J
B

C
L

G
L

K
L

D
H

H
H

L
H

PROTEIN (HEMAGGLUTININ (HA1 CHAIN))

PROTEIN (HEMAGGLUTININ (HA2 CHAIN))

PROTEIN (IMMUNOGLOBULIN IGG1-KAPPA ANTIBODY (LIGHT CHAIN))

PROTEIN (IMMUNOGLOBULIN IGG1-KAPPA ANTIBODY (HEAVY CHAIN))

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