SMTL ID : 1od9.1

N-terminal of Sialoadhesin in complex with Me-a-9-N-benzoyl-amino-9-deoxy-Neu5Ac (BENZ compound)

Coordinates

PDB Format

Method

X-RAY DIFFRACTION 2.10 Å

Oligo State

monomer

Ligands

1 x BND: methyl 5-acetamido-3,5,9-trideoxy-9-[(phenylcarbonyl)amino]-D-glycero-alpha-D-galacto-non-2-ulopyranosidonic acid(Non-covalent)

BND.1: 8 residues within 4Å: Chain A: W.2, Y.44, R.97, S.103, R.105, W.106, L.107, V.109 11 PLIP interactions: 11 interactions with chain A Hydrophobic interactions: A:W.2, A:W.106, A:L.107, A:V.109, A:V.109 Hydrogen bonds: A:R.105, A:R.105, A:L.107, A:L.107 Salt bridges: A:R.97, A:R.105

1 x SO4: SULFATE ION(Non-functional Binders)

SO4.2: 3 residues within 4Å: Chain A: K.58, K.62, R.65 7 PLIP interactions: 7 interactions with chain A Water bridges: A:K.62, A:K.62, A:R.65, A:R.65 Salt bridges: A:K.58, A:K.62, A:R.65

Links

RCSB   PDBe   PDBj   PDBsum   CATH   PLIP

Citation

Zaccai, N.R. et al., Structure-Guided Design of Sialic Acid-Based Siglec Inhibitors and Crystallographic Analysis in Complex with Sialoadhesin. Structure (2003)

Release Date

2003-05-16

Peptides

SIALOADHESIN: A

SMTL:PDB

SMTL Chain Id:
PDB Chain Id:

A
A

SIALOADHESIN

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