SMTL ID : 1m6p.1

EXTRACYTOPLASMIC DOMAIN OF BOVINE CATION-DEPENDENT MANNOSE 6-PHOSPHATE RECEPTOR

Coordinates

PDB Format

Method

X-RAY DIFFRACTION 1.80 Å

Oligo State

homo-dimer

Ligands

2 x MN: MANGANESE (II) ION(Non-covalent)

MN.1: 4 residues within 4Å: Chain A: E.99, D.101, R.109 Ligands: M6P.2 No protein-ligand interaction detected (PLIP) MN.3: 3 residues within 4Å: Chain B: D.101, R.109 Ligands: M6P.4 2 PLIP interactions: 1 interactions with chain B, 1 Ligand-Water interactions Metal complexes: B:D.101, H2O.5

2 x M6P: 6-O-phosphono-alpha-D-mannopyranose(Non-covalent)

M6P.2: 11 residues within 4Å: Chain A: Y.43, Q.64, Y.100, D.101, N.102, H.103, R.109, E.131, R.133, Y.141 Ligands: MN.1 15 PLIP interactions: 15 interactions with chain A Hydrogen bonds: A:Y.43, A:Q.64, A:Q.64, A:D.101, A:N.102, A:N.102, A:H.103, A:R.109, A:E.131, A:R.133, A:Y.141 Water bridges: A:K.71, A:T.73 Salt bridges: A:K.71, A:H.103 M6P.4: 11 residues within 4Å: Chain B: Y.43, Q.64, Y.100, D.101, N.102, H.103, R.109, E.131, R.133, Y.141 Ligands: MN.3 14 PLIP interactions: 14 interactions with chain B Hydrogen bonds: B:Y.43, B:Q.64, B:Q.64, B:D.101, B:N.102, B:N.102, B:H.103, B:R.109, B:E.131, B:R.133, B:Y.141 Water bridges: B:T.73 Salt bridges: B:H.103, B:R.109

Links

RCSB   PDBe   PDBj   PDBsum   CATH   PLIP

Citation

Roberts, D.L. et al., Molecular basis of lysosomal enzyme recognition: three-dimensional structure of the cation-dependent mannose 6-phosphate receptor. Cell(Cambridge,Mass.) (1998)

Release Date

1999-04-27

Peptides

CATION-DEPENDENT MANNOSE-6-PHOSPHATE RECEPTOR: AB

SMTL:PDB

SMTL Chain Id:
PDB Chain Id:

A
A

B
B

CATION-DEPENDENT MANNOSE-6-PHOSPHATE RECEPTOR

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