SMTL ID : 1lgb.1 (1 other biounit)

INTERACTION OF A LEGUME LECTIN WITH THE N2 FRAGMENT OF HUMAN LACTOTRANSFERRIN OR WITH THE ISOLATED BIANTENNARY GLYCOPEPTIDE: ROLE OF THE FUCOSE MOIETY

Coordinates

PDB Format

Method

X-RAY DIFFRACTION 3.30 Å

Oligo State

hetero-2-2-2-mer

Ligands

2 x NAG- NAG- BMA- MAN- NAG- GAL- MAN- NAG- FUC: beta-D-galactopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-2)-alpha-D-mannopyranose-(1-3)-[2-acetamido-2-deoxy-beta-D-glucopyranose-(1-2)-alpha-D-mannopyranose-(1-6)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose

NAG-NAG-BMA-MAN-NAG-GAL-MAN-NAG-FUC.1: 15 residues within 4Å: Chain A: N.39, Y.77, N.78, D.81, T.96, G.98, G.99, F.123, N.125 Chain B: G.29, A.30, E.31 Chain C: Q.20, F.45, N.47 2 PLIP interactions: 1 interactions with chain A, 1 interactions with chain B Hydrophobic interactions: A:Y.77 Hydrogen bonds: B:E.31 NAG-NAG-BMA-MAN-NAG-GAL-MAN-NAG-FUC.4: 15 residues within 4Å: Chain D: N.39, Y.77, N.78, D.81, T.96, G.98, G.99, F.123, N.125 Chain E: G.29, A.30, E.31 Chain F: Q.20, F.45, N.47 2 PLIP interactions: 1 interactions with chain D, 1 interactions with chain E Hydrophobic interactions: D:Y.77 Hydrogen bonds: E:E.31

2 x MN: MANGANESE (II) ION(Non-covalent)

MN.2: 4 residues within 4Å: Chain A: E.119, D.121, D.129, H.136 2 PLIP interactions: 2 interactions with chain A Metal complexes: A:E.119, A:D.129 MN.5: 4 residues within 4Å: Chain D: E.119, D.121, D.129, H.136 2 PLIP interactions: 2 interactions with chain D Metal complexes: D:E.119, D:D.129

2 x CA: CALCIUM ION(Non-covalent)

CA.3: 5 residues within 4Å: Chain A: D.81, D.121, F.123, N.125, D.129 3 PLIP interactions: 3 interactions with chain A Metal complexes: A:D.121, A:D.121, A:F.123 CA.6: 5 residues within 4Å: Chain D: D.81, D.121, F.123, N.125, D.129 3 PLIP interactions: 3 interactions with chain D Metal complexes: D:D.121, D:D.121, D:F.123

Links

RCSB   PDBe   PDBj   PDBsum   CATH   PLIP

Citation

Bourne, Y. et al., Structures of a legume lectin complexed with the human lactotransferrin N2 fragment, and with an isolated biantennary glycopeptide: role of the fucose moiety. Structure (1994)

Release Date

1994-08-31

Peptides

LEGUME ISOLECTIN II (ALPHA CHAIN): AD
LEGUME ISOLECTIN II (BETA CHAIN): BE
LACTOTRANSFERRIN (N2 FRAGMENT): CF

SMTL:PDB

SMTL Chain Id:
PDB Chain Id:

A
A

D
A

B
B

E
B

C
C

F
C

LEGUME ISOLECTIN II (ALPHA CHAIN)

LEGUME ISOLECTIN II (BETA CHAIN)

LACTOTRANSFERRIN (N2 FRAGMENT)

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