SMTL ID : 1hup.1

HUMAN MANNOSE BINDING PROTEIN CARBOHYDRATE RECOGNITION DOMAIN TRIMERIZES THROUGH A TRIPLE ALPHA-HELICAL COILED-COIL

Coordinates

PDB Format

Method

X-RAY DIFFRACTION 2.50 Å

Oligo State

homo-trimer

Ligands

12 x CA: CALCIUM ION(Non-covalent)

CA.1: 6 residues within 4Å: Chain A: D.81, E.85, N.108, E.113, D.114 Ligands: CA.3 5 PLIP interactions: 4 interactions with chain A, 1 Ligand-Water interactions Metal complexes: A:D.81, A:D.81, A:E.113, A:D.114, H2O.1 CA.2: 6 residues within 4Å: Chain A: E.105, N.107, E.113, N.125, D.126 Ligands: SO4.4 4 PLIP interactions: 4 interactions with chain A Metal complexes: A:E.105, A:E.113, A:D.126, A:D.126 CA.3: 3 residues within 4Å: Chain A: E.85, D.114 Ligands: CA.1 3 PLIP interactions: 3 interactions with chain A Metal complexes: A:E.85, A:D.114, A:D.114 CA.5: 3 residues within 4Å: Chain A: N.102, E.103, Q.123 2 PLIP interactions: 1 interactions with chain A, 1 Ligand-Water interactions Metal complexes: A:E.103, H2O.1 CA.6: 6 residues within 4Å: Chain B: D.81, E.85, N.108, E.113, D.114 Ligands: CA.8 5 PLIP interactions: 4 interactions with chain B, 1 Ligand-Water interactions Metal complexes: B:D.81, B:D.81, B:E.113, B:D.114, H2O.2 CA.7: 6 residues within 4Å: Chain B: E.105, N.107, E.113, N.125, D.126 Ligands: SO4.9 4 PLIP interactions: 4 interactions with chain B Metal complexes: B:E.105, B:E.113, B:D.126, B:D.126 CA.8: 3 residues within 4Å: Chain B: E.85, D.114 Ligands: CA.6 3 PLIP interactions: 3 interactions with chain B Metal complexes: B:E.85, B:D.114, B:D.114 CA.10: 3 residues within 4Å: Chain B: N.102, E.103, Q.123 2 PLIP interactions: 1 interactions with chain B, 1 Ligand-Water interactions Metal complexes: B:E.103, H2O.1 CA.11: 6 residues within 4Å: Chain C: D.81, E.85, N.108, E.113, D.114 Ligands: CA.13 5 PLIP interactions: 4 interactions with chain C, 1 Ligand-Water interactions Metal complexes: C:D.81, C:D.81, C:E.113, C:D.114, H2O.3 CA.12: 6 residues within 4Å: Chain C: E.105, N.107, E.113, N.125, D.126 Ligands: SO4.14 4 PLIP interactions: 4 interactions with chain C Metal complexes: C:E.105, C:E.113, C:D.126, C:D.126 CA.13: 3 residues within 4Å: Chain C: E.85, D.114 Ligands: CA.11 3 PLIP interactions: 3 interactions with chain C Metal complexes: C:E.85, C:D.114, C:D.114 CA.15: 3 residues within 4Å: Chain C: N.102, E.103, Q.123 2 PLIP interactions: 1 interactions with chain C, 1 Ligand-Water interactions Metal complexes: C:E.103, H2O.2

3 x SO4: SULFATE ION(Non-functional Binders)

SO4.4: 6 residues within 4Å: Chain A: E.105, N.107, E.113, N.125, D.126 Ligands: CA.2 3 PLIP interactions: 3 interactions with chain A Hydrogen bonds: A:N.107, A:N.107, A:N.125 SO4.9: 6 residues within 4Å: Chain B: E.105, N.107, E.113, N.125, D.126 Ligands: CA.7 3 PLIP interactions: 3 interactions with chain B Hydrogen bonds: B:N.107, B:N.107, B:N.125 SO4.14: 6 residues within 4Å: Chain C: E.105, N.107, E.113, N.125, D.126 Ligands: CA.12 3 PLIP interactions: 3 interactions with chain C Hydrogen bonds: C:N.107, C:N.107, C:N.125

Links

RCSB   PDBe   PDBj   PDBsum   CATH   PLIP

Citation

Sheriff, S. et al., Human mannose-binding protein carbohydrate recognition domain trimerizes through a triple alpha-helical coiled-coil. Nat.Struct.Biol. (1994)

Release Date

1995-10-15

Peptides

MANNOSE-BINDING PROTEIN: ABC

SMTL:PDB

SMTL Chain Id:
PDB Chain Id:

A
A

B
A

C
A

MANNOSE-BINDING PROTEIN