SMTL ID : 1h8u.1 (1 other biounit)

CRYSTAL STRUCTURE OF THE EOSINOPHIL MAJOR BASIC PROTEIN AT 1.8A: AN ATYPICAL LECTIN WITH A PARADIGM SHIFT IN SPECIFICITY

Coordinates

PDB Format

Method

X-RAY DIFFRACTION 1.80 Å

Oligo State

monomer

Ligands

5 x SO4: SULFATE ION(Non-functional Binders)

SO4.1: 5 residues within 4Å: Chain A: G.90, H.91, A.105, H.106, C.107 8 PLIP interactions: 8 interactions with chain A Hydrogen bonds: A:H.91, A:C.107 Water bridges: A:G.90, A:G.90, A:L.108, A:L.108 Salt bridges: A:H.91, A:H.106 SO4.2: 5 residues within 4Å: Chain A: R.65, S.87, R.88, H.91, R.104 8 PLIP interactions: 8 interactions with chain A Hydrogen bonds: A:R.88 Water bridges: A:G.90, A:R.104, A:R.104, A:R.104 Salt bridges: A:R.65, A:H.91, A:R.104 SO4.3: 4 residues within 4Å: Chain A: R.103, A.105, H.106, R.109 5 PLIP interactions: 5 interactions with chain A Hydrogen bonds: A:H.106 Water bridges: A:R.103, A:R.103 Salt bridges: A:R.103, A:R.109 SO4.4: 1 residues within 4Å: Chain A: R.63 1 PLIP interactions: 1 interactions with chain A Salt bridges: A:R.63 SO4.5: 2 residues within 4Å: Chain A: L.10, R.110 3 PLIP interactions: 3 interactions with chain A Water bridges: A:R.110, A:R.110 Salt bridges: A:R.110

2 x GOL: GLYCEROL(Non-functional Binders)

GOL.6: 2 residues within 4Å: Chain A: F.77, A.78 1 PLIP interactions: 1 interactions with chain A Hydrogen bonds: A:A.78 GOL.7: 2 residues within 4Å: Chain A: S.14, Q.15 2 PLIP interactions: 2 interactions with chain A Hydrogen bonds: A:S.14, A:Q.15

Links

RCSB   PDBe   PDBe-KB   PDBj   PDBsum   CATH   PLIP

Citation

Swaminathan, G.J. et al., Crystal Structure of the Eosinophil Major Basic Protein at 1.8A. An Atypical Lectin with a Paradigm Shift in Specificity. J.Biol.Chem. (2001)

Release Date

2001-07-17

Peptides

EOSINOPHIL GRANULE MAJOR BASIC PROTEIN 1: A

SMTL:PDB

SMTL Chain Id:
PDB Chain Id:

A
A

EOSINOPHIL GRANULE MAJOR BASIC PROTEIN 1

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