SMTL ID : 1d0h.1

THE HC FRAGMENT OF TETANUS TOXIN COMPLEXED WITH N-ACETYL-GALACTOSAMINE

Coordinates

PDB Format

Method

X-RAY DIFFRACTION 2.10 Å

Oligo State

monomer

Ligands

2 x A2G: 2-acetamido-2-deoxy-alpha-D-galactopyranose(Non-covalent)

A2G.1: 8 residues within 4Å: Chain A: K.297, D.301, Y.302, N.370, I.378, R.380, I.429 Ligands: SO4.3 7 PLIP interactions: 7 interactions with chain A Hydrophobic interactions: A:I.378 Hydrogen bonds: A:K.297, A:D.301, A:D.301 Water bridges: A:K.297, A:R.380 Salt bridges: A:R.380 A2G.2: 5 residues within 4Å: Chain A: K.351, Y.353, E.360, H.361, I.362 4 PLIP interactions: 4 interactions with chain A Hydrogen bonds: A:Y.353, A:I.362 Water bridges: A:Y.353, A:Y.353

1 x SO4: SULFATE ION(Non-functional Binders)

SO4.3: 4 residues within 4Å: Chain A: G.369, N.370, R.380 Ligands: A2G.1 4 PLIP interactions: 4 interactions with chain A Hydrogen bonds: A:N.370 Water bridges: A:Y.383, A:Y.383 Salt bridges: A:R.380

Links

RCSB   PDBe   PDBj   PDBsum   CATH   PLIP

Citation

Emsley, P. et al., The structures of the H(C) fragment of tetanus toxin with carbohydrate subunit complexes provide insight into ganglioside binding. J.Biol.Chem. (2000)

Release Date

2000-03-27

Peptides

PROTEIN (TETANUS TOXIN HC): A

SMTL:PDB

SMTL Chain Id:
PDB Chain Id:

A
A

PROTEIN (TETANUS TOXIN HC)